Initial Genome Scan of the NIMH Genetics Initiative Bipolar Pedigrees: Chromosomes 4, 7, 9, 18, 19, 20, and 21q

1997 ◽  
Vol 74 (3) ◽  
pp. 254-262 ◽  
Author(s):  
Sevilla D. Detera-Wadleigh ◽  
Judith A. Badner ◽  
Takeo Yoshikawa ◽  
Alan R. Sanders ◽  
Lynn R. Goldin ◽  
...  
Keyword(s):  
Genome Scan ◽  
Initial Genome

scholarly journals Linkage mapping of five genes on SSC12 in a Berkshire × Yorkshire cross (Brief report)

2008 ◽  
Vol 51 (1) ◽  
pp. 89-91
Author(s):  
M. Yu ◽  
M. F. Rothschild ◽  
J. Yang ◽  
S. Zhao ◽  
K. Li
Keyword(s):  
Quantitative Trait Loci ◽  
Quantitative Trait ◽  
Linkage Mapping ◽  
Genome Scan ◽  
Chromosome 12 ◽  
Generation Family ◽  
Trait Loci ◽  
Initial Genome

Abstract. three-generation family of pig was generated by an intercross between animals of two Berkshire grand sires and nine Yorkshire grand dams (BY), and a total of 525 F2 offspring were produced. The initial genome scan analysis identified suggestive quantitative trait loci (QTL) for fat traits on chromosome 12 (SSC12) (MALEK et al., 2001). Animals that were homozygous for Berkshire alleles had relatively less back fat than those with Yorkshire alleles, and heterozygotes were fattest for these QTL. The objective of this study was to further characterize these SSC12 QTL by mapping five additional genes (PSME3, GRB7, MAC30, RPS6KB1 and TAX1BP3) in the BY family and see if they were associated with fatness traits.

Initial genome scan of the NIMH genetics initiative bipolar pedigrees: Chromosomes 1, 6, 8, 10, and 12

1997 ◽  
Vol 74 (3) ◽  
pp. 247-253 ◽  
Author(s):  
John P. Rice ◽  
Alison Goate ◽  
Jeff T. Williams ◽  
Laura Bierut ◽  
David Dorr ◽  
...  
Keyword(s):  
Genome Scan ◽  
Initial Genome

Whole genome scan identifies several chromosomal regions linked to equine sarcoids

2012 ◽  
Vol 154 (1) ◽  
pp. 19-25 ◽  
Author(s):  
V. Jandova ◽  
J. Klukowska-Rötzler ◽  
G. Dolf ◽  
J. Janda ◽  
P. Roosje ◽  
...  
Keyword(s):  
Genome Scan ◽  
Whole Genome ◽  
Whole Genome Scan

scholarly journals Genetic Architecture of Testis and Seminal Vesicle Weights in Mice

Genetics ◽  
2001 ◽  
Vol 158 (1) ◽  
pp. 333-340 ◽  
Author(s):  
Isabelle Le Roy ◽  
Sylvie Tordjman ◽  
Danièle Migliore-Samour ◽  
Hervé Degrelle ◽  
Pierre L Roubertoux
Keyword(s):  
Seminal Vesicle ◽  
Inbred Strains ◽  
Genome Scan ◽  
Reproductive Organ ◽  
Seminal Vesicles ◽  
Total Variance ◽  
Chromosome 4 ◽  
Lod Score ◽  
Quantitative Genetic ◽  
Testicular Weight

Abstract Comparisons across 13 inbred strains of laboratory mice for reproductive organ (paired seminal vesicles and paired testes) weights indicated a very marked contrast between the C57BL/6By and NZB/BINJ mice. Subsequently these strains were selected to perform a quantitative genetic analysis and full genome scan for seminal vesicle and testis weights. An F2 population was generated. The quantitative genetic analyses indicated that each was linked to several genes. Sixty-six short sequences for length polymorphism were used as markers in the wide genome scan strategy. For weight of paired testes, heritability was 82.3% of the total variance and five QTL contributed to 72.8% of the total variance. Three reached a highly significant threshold (>4.5) and were mapped on chromosome X (LOD score 9.11), chromosome 4 (LOD score 5.96), chromosome 10 (LOD score 5.81); two QTL were suggested: chromosome 13 (LOD score 3.10) and chromosome 18 (LOD score 2.80). Heritability for weight of seminal vesicles was 50.7%. One QTL was mapped on chromosome 4 (LOD score 9.21) and contributed to 24.2% of the total variance. The distance of this QTL to the centromere encompassed the distance of the QTL linked with testicular weight on chromosome 4, suggesting common genetic mechanisms as expected from correlations in the F2. Both testis and seminal vesicle weights were associated with a reduction in the NZB/BINJ when this strain carried the YNPAR from CBA/H whereas the YNPAR from NZB/BINJ in the CBA/H strain did not modify reproductive organ weights, indicating that the YNPAR interacts with the non-YNPAR genes. The effects generated by this chromosomal region were significant but small in size.

scholarly journals A genome scan for selection signatures in Taihu pig breeds using next-generation sequencing

animal ◽  
2019 ◽  
Vol 13 (4) ◽  
pp. 683-693 ◽  
Author(s):  
Z. Wang ◽  
H. Sun ◽  
Q. Chen ◽  
X. Zhang ◽  
Q. Wang ◽  
...  
Keyword(s):  
Next Generation Sequencing ◽  
Genome Scan ◽  
Next Generation ◽  
Selection Signatures ◽  
Pig Breeds ◽  
A Genome ◽  
Generation Sequencing
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